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Search for "cancer invasion" in Full Text gives 2 result(s) in Beilstein Journal of Nanotechnology.

Examination of the relationship between viscoelastic properties and the invasion of ovarian cancer cells by atomic force microscopy

  • Mengdan Chen,
  • Jinshu Zeng,
  • Weiwei Ruan,
  • Zhenghong Zhang,
  • Yuhua Wang,
  • Shusen Xie,
  • Zhengchao Wang and
  • Hongqin Yang

Beilstein J. Nanotechnol. 2020, 11, 568–582, doi:10.3762/bjnano.11.45

Graphical Abstract
  • light on the biomechanical changes for early diagnosis of tumor transformation and progression at single-cell level. Keywords: atomic force microscopy (AFM); cancer invasion; cancer migration; ovarian cancer cells; viscoelasticity; Introduction Ovarian cancer is a lethal gynecological malignancy with
  • with cancer invasion after anticancer drug treatment [24][25]. Echinomycin serves as a potential therapeutic agent through the induction of cell apoptosis, which is typically used in the treatment of epithelial cancers, including ovary, breast and prostate cancers [26][27][28][29]. Inhibitory
  • mechanisms of cancer invasion and metastasis based on chemotherapy can be beneficial for both biomechanical research and clinical applications [30][31]. Therefore, the present study examined the elasticity and viscosity through AFM, and cell migration, invasion and microfilament density through cell
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Published 06 Apr 2020

The softening of human bladder cancer cells happens at an early stage of the malignancy process

  • Jorge R. Ramos,
  • Joanna Pabijan,
  • Ricardo Garcia and
  • Malgorzata Lekka

Beilstein J. Nanotechnol. 2014, 5, 447–457, doi:10.3762/bjnano.5.52

Graphical Abstract
  • . It is well established that actin filaments are mostly responsible for the mechanical properties of cells that are measured by the AFM. Therefore, there have been several attempts trying to show the correlation between the 2D-organization of actin filaments and cells stiffness in relation to cancer
  • invasion. The relation between the stiffness of cancer cells and the 2D-organization of the actin cytoskeleton has been reported for breast [3], thyroid [11] and ovarian [21] cancers. For stiffer cells, the actin filaments distribution usually revealed two types of filament organization, i.e., an actin
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Published 10 Apr 2014
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